Phytochemical and antibacterial in vitro analysis of millettia aurea extracts on neisseria gonorrhoeae

Authors

  • Eduardo Priceiro Universidade Rovuma - Mocambique
  • Lázaro Gonçalves Cuinica

Keywords:

Palavras-chave: Extratos de Millettia aurea, análise fitoquímica, atividade antimicrobiana, gonorreia.

Abstract

Alkaloids, flavonoids, tannins and saponins belong to secondary metabolites whose main activity is to defend and protect the plants that were produced. This work aims to analyze the bioactive substances of Millettia aurea extracts with inhibitory potential on bacteria that cause sexually transmitted diseases, focusing on gonorrhea. The methods used were analytical, which consisted in the identification of alkaloids, flavonoids, tannins and saponins, through the display of coloration and precipitate formation, as well as the UV/VIS spectrophotometric method for their quantification. Antibacterial analysis was performed in vitro, where Neisseria gonorrhoeae was grown on MacConkey agar medium and incubated for 1 day. Hallos of inhibition and percentage of lethality were measured. The minimum inhibitory concentration was determined through the lowest concentration of extracts that completely inhibited bacterial growth. The M. aurea root exhibited the presence of alkaloids, flavonoids and tannins, the alkaloids being the most concentrated. For the aqueous extract of the leaves of the same plant, the aforementioned metabolites also presented with maximum advantage in terms of concentrations, the flavonoids. The plant secondary metabolites already identified have a relationship with the antibacterial activity Neisseria gonorrhoeae

Downloads

Download data is not yet available.

Author Biography

Eduardo Priceiro, Universidade Rovuma - Mocambique

Autor:

Mestrando em Química de Produtos Naturais na Universidade Pedagógica de Maputo, Licenciado em Ensino de Química; Bacharelato em ensino de Química; Chefe de Repartição Académica do curso de Química e docente de Química Ambiental, Química orgânica e didácticas de Química na universidade Rovuma; pesquisador do Departamento.

Co-Autor:

Doutor em Farmacoquímica de Produtos Naturais e Sintéticos Bioativos pelo Instituto de Pesquisa de Fármacos e Medicamentos da UFPB em Brasil. Mestre em Toxicologia pelo Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto em Portugal. Diretor Adjunto de Pesquisa, Extensão e Inovação da FCNME. Linhas de pesquisa: Química Farmacêutica, Análise Fitoquímica, Farmacologia e Toxicologia de Produtos Naturais Bioativos.

Published

2021-04-02

How to Cite

Priceiro, E., & Cuinica, L. G. (2021). Phytochemical and antibacterial in vitro analysis of millettia aurea extracts on neisseria gonorrhoeae. REVISE – Integrative Journal on Technological Innovations in Health Sciences , 7(fluxocontinuo), 24–40. Retrieved from https://www3.ufrb.edu.br/index.php/revise/article/view/2052

Similar Articles

1 2 3 4 5 6 7 8 > >> 

You may also start an advanced similarity search for this article.